Metformin

Metformin is a medication commonly used in the management of type 2 diabetes. It is an oral antidiabetic medication with a long history of use.

• Metformin belongs to a class of medications called biguanides.
• It is a first-line option considered in many type 2 diabetes management plans.

• Blood glucose management in type 2 diabetes.
• Sometimes discussed in the context of insulin resistance and prediabetes.

• Metformin reduces glucose production in the liver and improves the body's sensitivity to insulin.
• It does not typically stimulate insulin secretion and is not associated with hypoglycemia when used alone.

• Digestive symptoms such as nausea, diarrhea, or appetite changes are most common, especially early in treatment.
• Taking the medication with food and starting at a low dose may reduce these effects.
• A rare but serious condition called lactic acidosis is associated with metformin in specific circumstances.

• Kidney function is typically assessed before and during treatment.
• Lactic acidosis is rare but serious and is more likely in people with significant kidney impairment or other risk factors.
• Contrast imaging procedures may require temporary discontinuation.
• These warnings are educational and not exhaustive.

• Kidney function and other medications affecting it are relevant.
• Alcohol use may increase certain risks.
• Discuss all medications and supplements with a clinician.

• Should I take this with food?
• What side effects are expected versus concerning?
• How will my kidney function be monitored?
• What should I do before any imaging procedures?